Summary
The International Collaboration on Cancer Reporting (ICCR) is a project which issues
datasets and guidelines for international standardisation of cancer reporting. This
review summarises the required and recommended elements of the datasets for prostate
core needle biopsies and transurethral resection (TURP) and enucleation specimens
of the prostate. To obtain as much information as possible from needle biopsies there
should be only one core in each specimen jar with the exception of saturation biopsies.
The gross description of the specimens should include core lengths of needle biopsies
and weight of resection specimens. The tumours should be classified according to the
4th World Health Organization (WHO) classification and graded both by Gleason scores
and the grouping of these in International Society of Urological Pathology (ISUP)
grades (Grade groups). Percent high-grade cancer is an optional component of the report.
Tumour extent in needle biopsies should be reported both by number of cores positive
for cancer and the linear extent measured in either millimetre or percent core involvement
by tumour. In needle biopsies where low-grade cancer is discontinuous and seen in
few cores, it is recommended that the tumour extent should be reported both by including
and subtracting intervening benign tissue. For resection specimens, the percentage
of the tissue area (or percentage of number of TURP chips) involved with cancer should
be estimated. Extraprostatic extension should be reported when seen, while the reporting
of perineural, seminal vesicle/ejaculatory duct and lymphovascular invasion is only
recommended. Intraductal carcinoma of the prostate (IDC-P) should be reported when
present, because of its strong link with aggressive cancer. The current recommendation
is that the IDC-P component should not be graded. The structured and standardised
reporting of prostate cancer contributes to safer and more efficient patient care
and facilitates the compilation and understanding of multiparametric diagnostic and
prognostic data.
Key words
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Article info
Publication history
Published online: November 23, 2018
Accepted:
October 1,
2018
Received in revised form:
September 25,
2018
Received:
September 12,
2018
Identification
Copyright
© 2018 Royal College of Pathologists of Australasia. Published by Elsevier B.V. All rights reserved.
